Product Name: SOD1-Tat (25-37)
Product Number: PE-01ANQ95
Size: 200 µg      Price:77.00
1 mg      $US154.00
5 mg      336.00
Peptide Name: SOD1-Tat (25-37)

Peptide Production Method: Solid-phase peptide synthesis

Peptide Origin: Homo sapiens

Peptide Sequence: YGRKKRRQRRRESNGPVKVWGSIK

Peptide Modifications N Terminus: Free amino

Peptide Modifications C Terminus: Amide

Peptide Molecular Mass Calculated: 2941.7 Da

Peptide Purity Percent after Synthesis and Purification: >95

Peptide Appearance: White powder

Peptide Form: Solid

Storage Conditions: -20°C

Scientific Background: SOD1 catalyzes the redox reaction that removes superoxide radicals which provides a defense agains oxygen toxicity. It is important in mamalian development and physiology.Tat sequence is used to allow the peptide to be transported into the cell
References

[1] Deng HX, Shi Y, Furukawa Y, Zhai H, Fu R, Liu E, Gorrie GH, Khan MS, Hung WY, Bigio EH, Lukas T, Dal Canto MC, O'Halloran TV, Siddique T. (2006) Conversion to the amyotrophic lateral sclerosis phenotype is associated with intermolecular linked insoluble aggregates of SOD1 in mitochondria. Proc Natl Acad Sci U S A. 103(18):7142-7. Epub 2006 Apr 24.; PMID:16636275

[2] Sherman L, Dafni N, Lieman-Hurwitz J, Groner Y. Nucleotide sequence and expression of human chromosome 21-encoded superoxide dismutase mRNA. Proc Natl Acad Sci U S A. 80(18):5465-9. PMID: 6577438