Product Name: KinSub1RADDSD
Product Number: PE-01ALT95
Size: 200 µg      Price:79.00
      $US
Peptide Name: KinSub1RADDSD

Product Use: For assaying the phosphotransferase activity of Casein protein-serine kinase 2 alpha/ alpha prime (CK2A, UniProt ID P68400). Used to assay CK2A.

Peptide Production Method: Solid-phase peptide synthesis

Peptide Origin: Based on CK2A substrate consensus sequence

Peptide Sequence: RRRADDSDDDDD

Peptide Modifications N Terminus: Free amino

Peptide Modifications C Terminus: Amide

Peptide Molecular Mass Calculated: 1449.4 Da

Peptide Purity Percent after Synthesis and Purification: >95

Peptide Appearance: White powder
Peptide Form: Solid

Storage Conditions: -20°C

Peptide Recommended Enzyme: CK2A

Scientific Background: Human CK2a1 is a protein-serine/threonine kinase of 391 amino acid length, with a predicted molecular mass of 45,144 Da. It is a member of the Other group of protein kinases in the CK2 family. This kinase is moderate to highly expressed in most tested human tissues. Orthologues of CK2a1 are amongst the most highly conserved protein kinases in animals, plants, fungi and unicellular eukaryotes. CK2a1 is activated by the CK2-beta regulatory subunit and also by binding p38a MAPK. CK2 is potently inhibited by heparin.