Product Name: KinSub1RADDSD
Product Number: PE-01ALT95
Size: | 200 µg | | Price: | 79.00 |
| | | $US | |
Peptide Name: KinSub1RADDSD
Product Use: For assaying the phosphotransferase activity of Casein protein-serine kinase 2 alpha/ alpha prime (CK2A, UniProt ID P68400). Used to assay CK2A.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Based on CK2A substrate consensus sequence
Peptide Sequence: RRRADDSDDDDD
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: Amide
Peptide Molecular Mass Calculated: 1449.4 Da
Peptide Purity Percent after Synthesis and Purification: >95
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Peptide Recommended Enzyme: CK2A
Scientific Background: Human CK2a1 is a protein-serine/threonine kinase of 391 amino acid length, with a predicted molecular mass of 45,144 Da. It is a member of the Other group of protein kinases in the CK2 family. This kinase is moderate to highly expressed in most tested human tissues. Orthologues of CK2a1 are amongst the most highly conserved protein kinases in animals, plants, fungi and unicellular eukaryotes. CK2a1 is activated by the CK2-beta regulatory subunit and also by binding p38a MAPK. CK2 is potently inhibited by heparin.