Product Name: MUC1 (142-961)
Product Number: PE-01AFU95
| Size: | 200 µg | Price: | 128.00 | |
| 1 mg | $US | 256.00 | ||
| 5 mg | 560.00 |
Peptide Name: MUC1 (142-961)
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: PDTRPAPGSTAPPAHGVTSAPDTRPAPGSTAPPAHGVTSA
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: Amide
Peptide Molecular Mass Calculated: 3754.9 Da
Peptide Purity Percent after Synthesis and Purification: >95
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: PDTRPAPGSTAPPAHGVTSAPDTRPAPGSTAPPAHGVTSA
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: Amide
Peptide Molecular Mass Calculated: 3754.9 Da
Peptide Purity Percent after Synthesis and Purification: >95
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Scientific Background: Mucin 1 is expressed on most epithelial cell surfaces and is an important biomarker for the diagnosis of early cancer.This sequence is the hallmark of MUC1 mucin. MUC1 is a highly glycosylated type I transmembrane glycoprotein with a unique extracellular domain consisting of a variable number of tandem repeats (VNTR) of this 20 amino acid peptide It is overexpressed on the cell surface of many human adenocarcinomas and hematological malignancies, including multiple myeloma and B-cell lymphoma, making MUC1 broadly applicable target for immunotherapeutic strategies. This 20 AA peptide is tandemly repeated many times in mucins produced by cancer cells
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