Product Name: HSP90a (255-268) KinSub
Product Number: PE-01ABK95
Size: | 200 µg | | Price: | 45.00 |
| 1 mg | | $US | 90.00 |
| 5 mg | | | 196.00 |
Peptide Name: HSP90a (255-268) KinSub
Product Use: For assaying the phosphotransferase activity of Casein protein-serine kinase 2 alpha/ alpha prime (UniProt ID P68400). Peptide is phosphorylated at S263 by casein kinase 2 (CK2) in vitro.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: KPEIEDVGSDEEEE
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: Amide
Peptide Molecular Mass Calculated: 1603.6 Da
Peptide Purity Percent after Synthesis and Purification: >95
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Peptide Recommended Enzyme: CK2a
Scientific Background: HSP90-alpha is a molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved in diverse cellular functions such as cycle control. It induces conformational changes in the client proteins in an ATP-dependent process as an ATPase, and causes their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.