Product Name: Histone H2A (22-30)
Product Number: PE-01ABG80
Size: | 200 µg | | Price: | 22.00 |
| 1 mg | | $US | 43.00 |
| 5 mg | | | 94.00 |
Peptide Name: Histone H2A (22-30)
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: AGLQFPVGR
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: Free carboxyl
Peptide Molecular Mass Calculated: 945.2 Da
Peptide Purity Percent after Synthesis and Purification: >80
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Scientific Background: HH2A is a core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.
References[1] Bartz R, Fan H, Zhang J, Innocent N, Cherrin C, Beck SC, Pei Y, Momose A, Jadhav V, Tellers DM, Meng F, Crocker LS, Sepp-Lorenzino L, Barnett SF. Structural studies of a peptide with immune modulating and direct antimicrobial activity. Biochem J. 2011 Apr 15;435(2):475-87. PMID: 21265735.