Product Name: Mastoparan-L (1-14)
Product Number: PE-01AAW95
| Size: | 200 µg | Price: | 45.00 | |
| 1 mg | $US | 90.00 | ||
| 5 mg | 196.00 |
Peptide Name: Mastoparan-L (1-14)
Product Use: Peptide induces mitochondrial membrane permeabilization via a cyclosporin A- (CsA-) inhibitable mechanism.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Wasp
Peptide Sequence: INLKALAALAKKIL
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: Amide
Peptide Molecular Mass Calculated: 1478.9 Da
Peptide Purity Percent after Synthesis and Purification: >95
Peptide Appearance: White powder
Peptide Form: Solid
Product Use: Peptide induces mitochondrial membrane permeabilization via a cyclosporin A- (CsA-) inhibitable mechanism.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Wasp
Peptide Sequence: INLKALAALAKKIL
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: Amide
Peptide Molecular Mass Calculated: 1478.9 Da
Peptide Purity Percent after Synthesis and Purification: >95
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
References
[1] Hori Y, Demura M, Iwadate M, Ulrich AS, Niidome T, Aoyagi H, Asakura T. Interaction of mastoparan with membranes studied by 1H-NMR spectroscopy in detergent micelles and by solid-state 2H-NMR and 15N-NMR spectroscopy in oriented lipid bilayers. Eur J Biochem. 2001 Jan;268(2):302-9. PMID: 11168364.
[2] Hirata Y, Nakahata N, Ohizumi Y. Identification of a 97-kDa mastoparan-binding protein involving in Ca(2+) release from skeletal muscle sarcoplasmic reticulum. Mol Pharmacol. 2000 Jun;57(6):1235-42. PMID: 10825395.
[3] Yajima Y, Uchino K, Ito H, Kawashima S. Mastoparan-stimulated prolactin secretion in rat pituitary GH3 cells involves activation of Gq/11 proteins. Endocrinology. 1997 May;138(5):1949-58. PMID: 9112392.
[1] Hori Y, Demura M, Iwadate M, Ulrich AS, Niidome T, Aoyagi H, Asakura T. Interaction of mastoparan with membranes studied by 1H-NMR spectroscopy in detergent micelles and by solid-state 2H-NMR and 15N-NMR spectroscopy in oriented lipid bilayers. Eur J Biochem. 2001 Jan;268(2):302-9. PMID: 11168364.
[2] Hirata Y, Nakahata N, Ohizumi Y. Identification of a 97-kDa mastoparan-binding protein involving in Ca(2+) release from skeletal muscle sarcoplasmic reticulum. Mol Pharmacol. 2000 Jun;57(6):1235-42. PMID: 10825395.
[3] Yajima Y, Uchino K, Ito H, Kawashima S. Mastoparan-stimulated prolactin secretion in rat pituitary GH3 cells involves activation of Gq/11 proteins. Endocrinology. 1997 May;138(5):1949-58. PMID: 9112392.
[4] Sukumar M, Ross EM, Higashijima T. A Gs-selective analog of the receptor-mimetic peptide mastoparan binds to Gs alpha in a kinked helical conformation. Biochemistry. 1997 Mar 25;36(12):3632-9. PIMD: 9132015.
[5] Higashijima T, Uzu S, Nakajima T, Ross EM. Mastoparan, a peptide toxin from wasp venom, mimics receptors by activating GTP-binding regulatory proteins (G proteins). Higashijima T, Uzu S, Nakajima T, Ross EM. J Biol Chem. 1988 May 15;263(14):6491-4. PMID: 3129426.
[5] Higashijima T, Uzu S, Nakajima T, Ross EM. Mastoparan, a peptide toxin from wasp venom, mimics receptors by activating GTP-binding regulatory proteins (G proteins). Higashijima T, Uzu S, Nakajima T, Ross EM. J Biol Chem. 1988 May 15;263(14):6491-4. PMID: 3129426.
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