Product Name: Beclin 2 (BECN1L1)
Product Number: AB-NN372-2
| Size: | 25 µg | Price: | 89.00 | |
| $US |
Target Full Name: Beclin-1-like protein 1
Target Alias: BECN1P1; Beclin-1 autophagy-related pseudogene 1; BECN2; Beclin-2; BECN1L1; Becn2; Beclin-2; PFM 2; PR domain zinc finger protein 5; PRDM 5; PR domain-containing protein 5; PRDM5; PRDM5_HUMAN; PR domain containing protein 5; BCS2
Product Type Specific: Autophagy protein pan-specific antibody
Antibody Code: NN372-2
Antibody Target Type: Pan-specific
Protein UniProt: A8MW95
Protein SigNET: A8MW95
Antibody Type: Polyclonal
Antibody Host Species: Rabbit
Target Alias: BECN1P1; Beclin-1 autophagy-related pseudogene 1; BECN2; Beclin-2; BECN1L1; Becn2; Beclin-2; PFM 2; PR domain zinc finger protein 5; PRDM 5; PR domain-containing protein 5; PRDM5; PRDM5_HUMAN; PR domain containing protein 5; BCS2
Product Type Specific: Autophagy protein pan-specific antibody
Antibody Code: NN372-2
Antibody Target Type: Pan-specific
Protein UniProt: A8MW95
Protein SigNET: A8MW95
Antibody Type: Polyclonal
Antibody Host Species: Rabbit
Antibody Immunogen Source: Synthetic peptide from the C-terminal of Mouse Beclin 2 (AA 410-421)
Production Method: Peptide Affinity purified
Antibody Modification: Unconjugated. Contact KInexus if you are interest in having the antibody biotinylated or coupled with fluorescent dyes.
Antibody Concentration: 1 mg/ml
Storage Buffer: Phosphate buffered saline, 50% glycerol, 0.09% sodium azide
Storage Conditions: For long term storage, keep frozen at -40°C or lower. Stock solution can be kept at +4°C for more than 3 months. Avoid repeated freeze-thaw cycles.
Product Use: Western blotting
Production Method: Peptide Affinity purified
Antibody Modification: Unconjugated. Contact KInexus if you are interest in having the antibody biotinylated or coupled with fluorescent dyes.
Antibody Concentration: 1 mg/ml
Storage Buffer: Phosphate buffered saline, 50% glycerol, 0.09% sodium azide
Storage Conditions: For long term storage, keep frozen at -40°C or lower. Stock solution can be kept at +4°C for more than 3 months. Avoid repeated freeze-thaw cycles.
Product Use: Western blotting
Antibody Dilution Recommended: WB (1:1000); optimal dilutions for assays should be determined by the user.
Antibody Potency: Detects a weak ~48 kDa protein band in mouse brain lysates by Western blotting.
Antibody Species Reactivity: Human | Mouse
Antibody Positive Control: A 1:1000 dilution of SPC-604 was sufficient for detection of Beclin 2 in 15 µg of Human HeLa cell lysates by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
Antibody Specificity: Very high
Antibody Cross Reactivity: No other prominent cross-reactive proteins in mouse brain lysates.
Related Product 1: Beclin 2 (BECN1L1) pan-specific antibody (Cat. No.: AB-NN372-1)
Antibody Potency: Detects a weak ~48 kDa protein band in mouse brain lysates by Western blotting.
Antibody Species Reactivity: Human | Mouse
Antibody Positive Control: A 1:1000 dilution of SPC-604 was sufficient for detection of Beclin 2 in 15 µg of Human HeLa cell lysates by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
Antibody Specificity: Very high
Antibody Cross Reactivity: No other prominent cross-reactive proteins in mouse brain lysates.
Related Product 1: Beclin 2 (BECN1L1) pan-specific antibody (Cat. No.: AB-NN372-1)
Scientific Background: Beclin 2 is a novel coiled-coil protein related to the autophagic Beclin 1 protein. It is thought to interact with Bcl-2, an anti-apoptotic protein, and is believed to function in autophagy. It has alson been found to mediate G protein-coupled receptro (GPCR) degradation (1).
© Kinexus Bioinformatics Corporation 2017