Product Name: PEX6
Product Number: AB-NN305-1
| Size: | 25 µg | Price: | 89.00 | |
| $US |
Target Full Name: Peroxisome assembly factor 2
Target Alias: PAF 2; Peroxin 6; Peroxisomal AAA type ATPase 1; Peroxisomal biogenesis factor 6; PXAAA1; peroxisomal-type ATPase 1; peroxisome biogenesis factor 6
Product Type Specific: PEX6 pan-specific antibody
Antibody Code: NN305-1
Antibody Target Type: Pan-specific
Protein UniProt: Q13608
Protein SigNET: Q13608
Antibody Type: Monoclonal
Antibody Host Species: Mouse
Antibody Ig Isotype Clone: IgG1
Target Alias: PAF 2; Peroxin 6; Peroxisomal AAA type ATPase 1; Peroxisomal biogenesis factor 6; PXAAA1; peroxisomal-type ATPase 1; peroxisome biogenesis factor 6
Product Type Specific: PEX6 pan-specific antibody
Antibody Code: NN305-1
Antibody Target Type: Pan-specific
Protein UniProt: Q13608
Protein SigNET: Q13608
Antibody Type: Monoclonal
Antibody Host Species: Mouse
Antibody Ig Isotype Clone: IgG1
Antibody Immunogen Source: Fusion protein amino acids 2-294 (N-terminus) of human PEX6. Rat: 82% identity (243/293 amino acids identical). Mouse: 82% identity (244/294 amino acids identical). <50% identity with other PEX proteins.
Production Method: Protein G purified
Antibody Modification: Unconjugated. Contact KInexus if you are interest in having the antibody biotinylated or coupled with fluorescent dyes.
Antibody Concentration: 1 mg/ml
Storage Buffer: Phosphate buffered saline pH 7.4, 50% glycerol, 0.1% sodium azide
Storage Conditions: For long term storage, keep frozen at -40°C or lower. Stock solution can be kept at +4°C for more than 3 months. Avoid repeated freeze-thaw cycles.
Production Method: Protein G purified
Antibody Modification: Unconjugated. Contact KInexus if you are interest in having the antibody biotinylated or coupled with fluorescent dyes.
Antibody Concentration: 1 mg/ml
Storage Buffer: Phosphate buffered saline pH 7.4, 50% glycerol, 0.1% sodium azide
Storage Conditions: For long term storage, keep frozen at -40°C or lower. Stock solution can be kept at +4°C for more than 3 months. Avoid repeated freeze-thaw cycles.
Product Use: Western blotting | ICC/Immunofluorescence
Antibody Dilution Recommended: WB (1:1000); optimal dilutions for assays should be determined by the user.
Antibody Potency: In mouse brain lysates, this antibody detects a ~100 kDa protein by Western blotting.
Antibody Species Reactivity: Human | Rat
Antibody Positive Control: 1 µg/ml of SMC-470 was sufficient for detection of PEX6 in 20 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
Antibody Specificity: Very high
Antibody Dilution Recommended: WB (1:1000); optimal dilutions for assays should be determined by the user.
Antibody Potency: In mouse brain lysates, this antibody detects a ~100 kDa protein by Western blotting.
Antibody Species Reactivity: Human | Rat
Antibody Positive Control: 1 µg/ml of SMC-470 was sufficient for detection of PEX6 in 20 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
Antibody Specificity: Very high
Scientific Background: This gene encodes a member of the AAA (ATPases associated with diverse cellular activities) family of ATPases. This member is a predominantly cytoplasmic protein, which plays a direct role in peroxisomal protein import and is required for PTS1 (peroxisomal targeting signal 1, a C-terminal tripeptide of the sequence ser-lys-leu) receptor activity. Mutations in this gene cause peroxisome biogenesis disorders of complementation group 4 and complementation group 6.
© Kinexus Bioinformatics Corporation 2017