Product Name: GABA-A Receptor Epsilon
Product Number: AB-NN255-1
Size: | 25 µg | | Price: | 89.00 |
| | | $US | |
Target Full Name: Gamma-aminobutyric acid receptor subunit epsilon
Target Alias: Gamma-aminobutyric acid receptor epsilon subunit; GABRE
Product Type Specific: Chloride channel pan-specific antibody
Antibody Code: NN255-1
Antibody Target Type: Pan-specific
Protein UniProt: P78334 Protein SigNET: P78334 Antibody Type: Monoclonal
Antibody Host Species: Mouse
Antibody Ig Isotype Clone: IgG2A
Antibody Immunogen Source: Fusion protein amino acids 27-253 (Extracellular N-terminus) of human GABA-A Receptor Epsilon
Production Method: Protein G purified
Antibody Modification: Unconjugated. Contact KInexus if you are interest in having the antibody biotinylated or coupled with fluorescent dyes.
Antibody Concentration: 1 mg/ml
Storage Buffer: Phosphate buffered saline pH7.4, 50% glycerol, 0.1% sodium azide
Storage Conditions: For long term storage, keep frozen at -40°C or lower. Stock solution can be kept at +4°C for more than 3 months. Avoid repeated freeze-thaw cycles.
Product Use: Western blotting | Immunohistochemistry | ICC/Immunofluorescence
Antibody Dilution Recommended: WB (1:1000); optimal dilutions for assays should be determined by the user.
Scientific Background: The GABA-A receptor is a member of the superfamily of fast acting ligand-gated ion channels. The individual subunits of these receptors have similar sequences and structural features (1). GABA-A receptors are the major fast inhibitory neurotransmitter gated ion channels in the brain (2). Brainstem expression of GABA-A Receptor, Epsilon, is upregulated during pregnancy (3).