Product Name: EAAC1
Product Number: AB-NN244-1
| Size: | 25 µg | Price: | 89.00 | |
| $US |
Target Full Name: Excitatory amino acid transporter 3
Target Alias: Excitatory amino-acid carrier 1; excitatory amino acid transporter 3; EAAT3; Neuronal and epithelial glutamate transporter; Sodium-dependent glutamate/aspartate transporter 3; solute carrier family 1 member 1 and Slc1a1
Product Type Specific: Amino acid transport protein pan-specific antibody
Antibody Code: NN244-1
Antibody Target Type: Pan-specific
Protein UniProt: P43005
Protein SigNET: P43005
Antibody Type: Monoclonal
Antibody Host Species: Mouse
Antibody Ig Isotype Clone: IgG1
Target Alias: Excitatory amino-acid carrier 1; excitatory amino acid transporter 3; EAAT3; Neuronal and epithelial glutamate transporter; Sodium-dependent glutamate/aspartate transporter 3; solute carrier family 1 member 1 and Slc1a1
Product Type Specific: Amino acid transport protein pan-specific antibody
Antibody Code: NN244-1
Antibody Target Type: Pan-specific
Protein UniProt: P43005
Protein SigNET: P43005
Antibody Type: Monoclonal
Antibody Host Species: Mouse
Antibody Ig Isotype Clone: IgG1
Antibody Immunogen Source: Fusion protein amino acids 1-524 (full length) of human EAAC1
Production Method: Protein G purified
Antibody Modification: Unconjugated. Contact KInexus if you are interest in having the antibody biotinylated or coupled with fluorescent dyes.
Antibody Concentration: 1 mg/ml
Storage Buffer: Phosphate buffered saline pH7.4, 50% glycerol, 0.09% sodium azide
Storage Conditions: For long term storage, keep frozen at -40°C or lower. Stock solution can be kept at +4°C for more than 3 months. Avoid repeated freeze-thaw cycles.
Product Use: Western blotting | Immunoprecipitation
Production Method: Protein G purified
Antibody Modification: Unconjugated. Contact KInexus if you are interest in having the antibody biotinylated or coupled with fluorescent dyes.
Antibody Concentration: 1 mg/ml
Storage Buffer: Phosphate buffered saline pH7.4, 50% glycerol, 0.09% sodium azide
Storage Conditions: For long term storage, keep frozen at -40°C or lower. Stock solution can be kept at +4°C for more than 3 months. Avoid repeated freeze-thaw cycles.
Product Use: Western blotting | Immunoprecipitation
Antibody Dilution Recommended: WB (1:1000); optimal dilutions for assays should be determined by the user.
Antibody Potency: Detects a ~60 kDa protein in cell and tissue lysates by Western blotting.
Antibody Species Reactivity: Human | Rat
Antibody Positive Control: 5 µg of SMC-406 was sufficient for immunoprecipitation of EAAC1 from 50 µg of rat brain lysate.
Antibody Potency: Detects a ~60 kDa protein in cell and tissue lysates by Western blotting.
Antibody Species Reactivity: Human | Rat
Antibody Positive Control: 5 µg of SMC-406 was sufficient for immunoprecipitation of EAAC1 from 50 µg of rat brain lysate.
Scientific Background: SLC1A1/EAAT3/EAAC1, a member of this transporter family, is expressed throughout the body, particularly in brain, intestine, liver, heart and kidney. Functional defects of the SLC1A1 gene are found in patients of dicarboxylicamino aciduria.
References
[1] Smith C. P. et al., (1994) Genomics 20:335-336.
[2] Kanai Y., and Hediger M. A. (1992) Nature 360:467-471.
[1] Smith C. P. et al., (1994) Genomics 20:335-336.
[2] Kanai Y., and Hediger M. A. (1992) Nature 360:467-471.
© Kinexus Bioinformatics Corporation 2017