Product Name: Ankyrin-B
Product Number: AB-NN196-1
| Size: | 25 µg | Price: | 89.00 | |
| $US |
Target Full Name: Ankyrin-2
Target Alias: ANK-2; ANK2; Ankyrin 2; Ankyrin nonerythroid; Brain ankyrin; non-erythroid ankyrin; Ankyrin-B
Product Type Specific: Cytoskeletal protein pan-specific antibody
Antibody Code: NN196-1
Antibody Target Type: Pan-specific
Protein UniProt: Q01484
Protein SigNET: Q01484
Antibody Type: Monoclonal
Antibody Host Species: Mouse
Antibody Ig Isotype Clone: IgG1
Antibody Immunogen Source: Synthetic peptide amino acids 203-496 of human Ankyrin-B
Target Alias: ANK-2; ANK2; Ankyrin 2; Ankyrin nonerythroid; Brain ankyrin; non-erythroid ankyrin; Ankyrin-B
Product Type Specific: Cytoskeletal protein pan-specific antibody
Antibody Code: NN196-1
Antibody Target Type: Pan-specific
Protein UniProt: Q01484
Protein SigNET: Q01484
Antibody Type: Monoclonal
Antibody Host Species: Mouse
Antibody Ig Isotype Clone: IgG1
Antibody Immunogen Source: Synthetic peptide amino acids 203-496 of human Ankyrin-B
Production Method: Protein G purified
Antibody Modification: Unconjugated. Contact KInexus if you are interest in having the antibody biotinylated or coupled with fluorescent dyes.
Antibody Concentration: 1 mg/ml
Storage Buffer: Phosphate buffered saline pH7.4, 50% glycerol, 0.09% sodium azide
Storage Conditions: For long term storage, keep frozen at -40°C or lower. Stock solution can be kept at +4°C for more than 3 months. Avoid repeated freeze-thaw cycles.
Product Use: Western blotting | Immunohistochemistry | ICC/Immunofluorescence
Antibody Dilution Recommended: WB (1:1000), IHC (1:200), ICC/IF (1:200); optimal dilutions for assays should be determined by the user.
Antibody Modification: Unconjugated. Contact KInexus if you are interest in having the antibody biotinylated or coupled with fluorescent dyes.
Antibody Concentration: 1 mg/ml
Storage Buffer: Phosphate buffered saline pH7.4, 50% glycerol, 0.09% sodium azide
Storage Conditions: For long term storage, keep frozen at -40°C or lower. Stock solution can be kept at +4°C for more than 3 months. Avoid repeated freeze-thaw cycles.
Product Use: Western blotting | Immunohistochemistry | ICC/Immunofluorescence
Antibody Dilution Recommended: WB (1:1000), IHC (1:200), ICC/IF (1:200); optimal dilutions for assays should be determined by the user.
Antibody Potency: Detects a ~200 kDa protein in cell and tissue lysates by Western blotting.
Antibody Species Reactivity: Human | Mouse | Rat
Antibody Positive Control: 1 µg/ml of SMC-400 was sufficient for detection of Ankyrin-B in 20 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
Antibody Cross Reactivity: No cross reactivity against Ankyrin-G.
Related Product 2: Ankyrin R pan-specific antibody (Cat. No.: AB-NN195-1)
Related Product 3: Ankyrin-G pan-specific antibody (Cat. No.: AB-NN197-1)
Related Product 4: Ankyrin-B pan-specific antibody (Cat. No.: AB-NN196-2)
Antibody Species Reactivity: Human | Mouse | Rat
Antibody Positive Control: 1 µg/ml of SMC-400 was sufficient for detection of Ankyrin-B in 20 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
Antibody Cross Reactivity: No cross reactivity against Ankyrin-G.
Related Product 2: Ankyrin R pan-specific antibody (Cat. No.: AB-NN195-1)
Related Product 3: Ankyrin-G pan-specific antibody (Cat. No.: AB-NN197-1)
Related Product 4: Ankyrin-B pan-specific antibody (Cat. No.: AB-NN196-2)
Scientific Background: Ankyrins are a family of adaptor proteins that mediate the attachment of integral membrane proteins to the spectrin-actin based membrane skeleton (1). Ankyrins have binding sites for the beta subunit of spectrin and at least 12 families of integral membrane proteins. This linkage is required to maintain the integrity of the plasma membranes and to anchor specific ion channels, ion exchangers and ion transporters in the plasma membrane.
© Kinexus Bioinformatics Corporation 2017